| INTERNATIONAL FEDERATION OF ACCOUNTANTS | New York | B50P Education | $43.8M | 19 |
| HARVARD CLUB OF NEW YORK CITY | New York | — | $43.7M | 7 |
| GRAND STREET SETTLEMENT INC | New York | P200 Human Services | $43.6M | 7 |
| PUERTO RICAN FAMILY INSTITUTE INC | New York | P200 Human Services | $43.6M | 7 |
| ELIZABETH L ELTING FOUNDATION | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $43.6M | 0 |
| WELFARE FUND TEAMSTERS LOCAL 237 IBT GEN | New York | — | $43.5M | 11 |
| TATE AMERICAS FOUNDATION | New York | A115 Arts, Culture & Humanities | $43.5M | 3 |
| MIDWAY LIVING INC | Brooklyn | L40 Housing & Shelter | $43.5M | 2 |
| HOUSING WORKS HEALTH SERVICES III INC | Brooklyn | G810 Diseases, Disorders & Medical Disciplines | $43.4M | 8 |
| ALLIANCE OF WESTERN NEW YORK BENEFIT | Niagara Falls | Y43 Mutual & Membership Benefit | $43.4M | 0 |
| MUSEUM OF CHINESE IN AMERICA | New York | A500 Arts, Culture & Humanities | $43.3M | 4 |
| SUNNYSIDE HOME CARE PROJECT INC | Long Island City | E920 Health Care | $43.1M | 4 |
| COORDINATED CARE SERVICES INC | Rochester | — | $43.1M | 10 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF LONG ISLAND INC | Glen Cove | P270 Human Services | $43.1M | 9 |
| DELAWARE VALLEY HOSPITAL INC | Walton | E22Z Health Care | $43.1M | 11 |
| A Very Special Place Inc | Staten Island | — | $43M | 3 |
| DIA CENTER FOR THE ARTS INC | New York | A200 Arts, Culture & Humanities | $42.8M | 10 |
| UNITED FEDERATION OF TEACHERS HEALTH CAR | New York | — | $42.8M | 1 |
| UNISWAP FOUNDATION | New York | R12 Civil Rights, Social Action & Advocacy | $42.8M | 5 |
| BronxCare Special Care Center Inc | Bronx | E32Z Health Care | $42.8M | 9 |
| NEW YORK CITY & VICINITY DISTRICT | New York | — | $42.8M | 108 |
| AMERICAN JEWISH WORLD SERVICE INC | New York | Q300 International, Foreign Affairs & National Security | $42.7M | 14 |
| EXPLORE CHARTER SCHOOLS OF BROOKLYN | Brooklyn | B29 Education | $42.7M | 12 |
| VAUGHN COLLEGE OF AERONAUTICS | Flushing | B42 Education | $42.6M | 10 |
| BIKUR CHOLIM INC | Airmont | E86Z Health Care | $42.6M | 7 |
| PARKER JEWISH INSTITUTE FOR HEALTH CARE | New Hyde Park | E110 Health Care | $42.6M | 3 |
| THE CORNING MUSEUM OF GLASS | Corning | — | $42.5M | 8 |
| INT'L ALLIANCE OF THEATRICAL STAGE | New York | — | $42.5M | 26 |
| THE SUZANNE AND THOMAS MURPHY FOUNDATION | Melville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $42.4M | 0 |
| 1199SEIU LABOR MANAGEMENT | New York | — | $42.3M | 11 |
| PARCARE COMMUNITY HEALTH NETWORK INC | Brooklyn | E32 Health Care | $42.3M | 8 |
| NYSARC INC ONEIDA-LEWIS CHAPTER | Utica | — | $42.2M | 3 |
| THE CENTER FOR FAMILY SUPPORT INC | New York | P82 Human Services | $42.2M | 11 |
| EMMA WILLARD SCHOOL | Troy | B250 Education | $42.1M | 7 |
| HEAD INJURY ASSOCIATION INC | Hauppauge | G48Z Diseases, Disorders & Medical Disciplines | $41.9M | 0 |
| ALLIANCE UNIVERSITY | New York | B420 Education | $41.9M | 10 |
| TIGER GLOBAL IMPACT VENTURES INC | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $41.9M | 0 |
| UNITED ODD FELLOW AND REBEKAH HOME | Bronx | E91Z Health Care | $41.8M | 9 |
| NEW YORK CITY CRIMINAL JUSTICE AGENCY | New York | — | $41.7M | 7 |
| METROPOLITAN JEWISH HOME CARE INC | New York | E92 Health Care | $41.6M | 9 |
| LOCAL 298 HEALTH FUND I | Valley Stream | — | $41.6M | 0 |
| JAMAICA HOSPITAL NURSING HOME | Jamaica | — | $41.5M | 8 |
| GLENN GREENBERG AND LINDA VESTER | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $41.5M | 0 |
| Bingle Foundation | Saratoga Springs | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $41.4M | 0 |
| CO-IMPACT PHILANTHROPIC FUNDS INC | New York | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $41.3M | 14 |
| FIT STUDENT HOUSING CORPORATION | New York | — | $41.2M | 5 |
| GROWING UP GREEN CHARTER SCHOOLS | Jamaica | B29 Education | $41.1M | 7 |
| NYSARC INC ROCKLAND COUNTY CHAPTER | Valley Cottage | P820 Human Services | $41.1M | 8 |
| God's Love We Deliver Inc | New York | K36Z Food, Agriculture & Nutrition | $41.1M | 10 |
| NORTHERN CREDIT UNION | Watertown | W61 Public & Societal Benefit | $41.1M | 3 |
