| EASTERN ATLANTIC STATES CARPENTERS TECHNICAL CENTERS | Philadelphia | J22Z Employment | $21.3M | 8 |
| BERKS COMMUNITY HEALTH CENTER | Reading | E32 Health Care | $21.3M | 7 |
| FUTURE OF LIFE INSTITUTE | Narberth | U99 Science & Technology | $21.3M | 6 |
| GSLPG INC | Allentown | E21 Health Care | $21.2M | 0 |
| THE COMMUNITY AT ROCKHILL | Sellersville | E50 Health Care | $21.2M | 8 |
| LINCOLN LEARNING SOLUTIONS INC | Aliquippa | B192 Education | $21.2M | 13 |
| NATIONAL KITCHEN & BATH ASSOCIATION | Bethlehem | — | $21.1M | 11 |
| FRANKLIN TOWNE CHARTER ELEMENTARY SCHOOL | Philadelphia | B29 Education | $21.1M | 4 |
| COMMUNITY LIFE TEAM | Harrisburg | E220 Health Care | $21M | 14 |
| ENDLESS MOUNTAINS HEALTH SYSTEMS INC | Montrose | E220 Health Care | $21M | 8 |
| West Oak Lane Charter School | Philadelphia | B290 Education | $20.9M | 9 |
| ASBURY HEALTH CENTER | Pittsburgh | P750 Human Services | $20.9M | 7 |
| JACK M BARRACK HEBREW ACADEMY | Bryn Mawr | — | $20.9M | 6 |
| LANCASTER EMERGENCY MEDICAL SERVICES ASSOCIATION | Lancaster | E62 Health Care | $20.8M | 8 |
| University City Science Center | Philadelphia | U050 Science & Technology | $20.8M | 12 |
| MERAKEY DELAWARE COUNTY | Lafayette Hill | F30Z Mental Health & Crisis Intervention | $20.8M | 11 |
| GOOD SAMARITAN PHYSICIAN SERVICES | York | E30 Health Care | $20.8M | 13 |
| GREATER PHILADELPHIA COMMUNITY ALLIANCE | Philadelphia | P33Z Human Services | $20.8M | 4 |
| NEW HERITAGE TOWERS | Warminster | — | $20.7M | 8 |
| CHRISTOPHER COLUMBUS CHARTER SCHOOL | Philadelphia | B24 Education | $20.7M | 2 |
| MORAVIAN VILLAGE OF BETHLEHEM | Bethlehem | L22 Housing & Shelter | $20.7M | 5 |
| GRANT FOUNDATION INC | Pittsburgh | Q300 International, Foreign Affairs & National Security | $20.7M | 4 |
| ECUMENICAL ENTERPRISES INC | Dallas | P120 Human Services | $20.7M | 13 |
| BERKS COUNTY COMMUNITY FOUNDATION INC | Reading | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $20.7M | 2 |
| KIPP WEST PHILADELPHIA CHARTER SCHOOL | Philadelphia | B29 Education | $20.6M | 7 |
| UPMC Greene | Waynesburg | E20 Health Care | $20.6M | 13 |
| CETRONIA AMBULANCE CORPS INC | Allentown | — | $20.6M | 7 |
| VIECARE BUTLER LLC | Cranberry Township | L20 Housing & Shelter | $20.5M | 5 |
| UNITED COMMUNITY INDEPENDENCE PROGRAMS | Meadville | P82Z Human Services | $20.5M | 4 |
| DICK'S SPORTING GOODS FOUNDATION | Coraopolis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $20.5M | 0 |
| PENNSYLVANIA PROFESSIONAL LIABILITY JOINT UNDERWRITING ASSOCIATION | Dresher | — | $20.5M | 2 |
| LANCASTER COUNTRY DAY SCHOOL | Lancaster | B24Z Education | $20.5M | 7 |
| COMMUNITY NURSES HOME HEALTH & HOSPICE INC | St Marys | E92Z Health Care | $20.4M | 2 |
| BOARD OF DIRECTORS OF THE ROUSE ESTATE | Youngsville | E90Z Health Care | $20.4M | 3 |
| AMERICAN PHILOSOPHICAL SOCIETY | Philadelphia | A700 Arts, Culture & Humanities | $20.4M | 9 |
| TRUENORTH WELLNESS SERVICES | Hanover | F220 Mental Health & Crisis Intervention | $20.4M | 6 |
| UNITED FOOD & COMMERCIAL WORKERS LOCAL 1776 | Plymouth Meeting | — | $20.3M | 3 |
| THE WAWA FOUNDATION INC | Wawa | P20 Human Services | $20.3M | 0 |
| PENNSYLVANIA ASSOCIATION OF REGIONAL FOOD BANKS | Pittsburgh | — | $20.3M | 1 |
| THE CHAMPLIN FOUNDATION | Pittsburgh | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $20.3M | 13 |
| SCOTT FOUNDATION INC | Greensburg | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $20.2M | 0 |
| NONPROFIT PARTNERS INC | Johnstown | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $20.2M | 3 |
| ACTS SIGNATURE COMMUNITY SERVICES INC | Fort Washington | E92 Health Care | $20.2M | 10 |
| THE SUMMIT SCHOOL | Herman | B200 Education | $20.2M | 2 |
| PROSPECTUS ASSOCIATES INC | Reading | P80Z Human Services | $20.2M | 5 |
| CHANDLER HALL HEALTH SERVICES INC | Newtown | E210 Health Care | $20.1M | 7 |
| TOWER HEALTH AT HOME FKA TOWER HEALTH AT HOME - BERKS | Reading | E92Z Health Care | $20.1M | 9 |
| GERMANTOWN HOME | Philadelphia | E910 Health Care | $20.1M | 5 |
| OLD ORDER AMISH HELPING PROGRAM | Elizabethville | P60 Human Services | $20.1M | 3 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA PRACTICE ASSOCIATION | Philadelphia | F32Z Mental Health & Crisis Intervention | $20.1M | 10 |
