| PRESIDENT-BOARD OF TRUSTEES SANTA CLARA COLLEGE | Santa Clara | B430 Education | $679.7M | 19 |
| COMMUNITY MEMORIAL HEALTH SYSTEM | Ventura | E220 Health Care | $678M | 25 |
| PUBLIC HEALTH FOUNDATION ENTERPRISES INC | City Of Industry | — | $670.2M | 10 |
| CHILD CARE RESOURCE CENTER INC | Chatsworth | O40Z Youth Development | $668.3M | 14 |
| HEALTHCARE LA IPA | Thousand Oaks | E21 Health Care | $665.1M | 1 |
| MARIN GENERAL HOSPITAL | Greenbrae | E220 Health Care | $661.9M | 15 |
| Sharp Chula Vista Medical Center | San Diego | E220 Health Care | $659.9M | 21 |
| Emanate Health Medical Center | Covina | E220 Health Care | $656M | 7 |
| THE SCRIPPS RESEARCH INSTITUTE | La Jolla | H92 Medical Research | $641.1M | 15 |
| UNITED FOOD AND COMMERCIAL WORKERS UNIONS AND FOOD EMPLOYERS BENEFIT FUND | Cypress | — | $640.9M | 7 |
| SAINT AGNES MEDICAL CENTER | Fresno | E220 Health Care | $638.9M | 14 |
| South Central Los Angeles Regional Center for Dev Disabled Persons Inc | Los Angeles | P82Z Human Services | $637M | 10 |
| Central Valley Regional Center | Fresno | P820 Human Services | $630.5M | 7 |
| UNIVERSITY OF SAN DIEGO | San Diego | — | $622.2M | 27 |
| San Joaquin Community Hospital dba Adventist Health Bakersfield | Bakersfield | E220 Health Care | $621.3M | 22 |
| CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO INC | San Ysidro | E32Z Health Care | $615.9M | 19 |
| Glendale Adventist Medical Center dba Adventist Health Glendale | Glendale | E220 Health Care | $586.2M | 21 |
| COMMONSPIRIT HEALTH OPERATING INVESTMENT POOL LLC | San Francisco | X22 Religion-Related | $584.5M | 2 |
| JOHN MUIR PHYSICIAN NETWORK | Walnut Creek | E32Z Health Care | $582M | 11 |
| UNIVERSITY OF CALIFORNIA SAN FRANCISCO FOUNDATION | San Francisco | B110 Education | $574.9M | 7 |
| PAC-12 CONFERENCE | San Ramon | N60Z Recreation & Sports | $566.6M | 26 |
| SUTTER VISITING NURSE ASSOCIATION AND HOSPICE | Sacramento | P74 Human Services | $559.2M | 19 |
| University of San Francisco | San Francisco | B430 Education | $553M | 18 |
| GOLDEN GATE REGIONAL CENTER INC | San Francisco | P820 Human Services | $545.9M | 5 |
| TRI-COUNTIES ASSOCIATION FOR THE DEVELOPMENTALLY DISABLED INC | Santa Barbara | — | $544.3M | 7 |
| NATIONAL UNIVERSITY | San Diego | B430 Education | $544.2M | 24 |
| EASTER SEALS SOUTHERN CALIFORNIA INC | Irvine | — | $535.5M | 8 |
| STANFORD HEALTH CARE TRI-VALLEY | Livermore | E200 Health Care | $531.8M | 23 |
| UFCW & EMPLOYERS BENEFIT TRUST | Concord | — | $529M | 7 |
| PATELCO CREDIT UNION | Dublin | — | $527.5M | 14 |
| University of the Pacific | Stockton | B430 Education | $526.9M | 31 |
| JOINT BOARD OF TRUSTEES SOUTHWEST CARPENTERS HEALTH AND WELFARE TRUST | Los Angeles | — | $526.2M | 7 |
| VALLEY PRESBYTERIAN HOSPITAL | Van Nuys | E220 Health Care | $517M | 22 |
| HENRY MAYO NEWHALL MEMORIAL HOSPITAL | Valencia | E220 Health Care | $512.2M | 15 |
| UNIVERSITY OF CALIFORNIA BERKELEY FOUNDATION | Berkeley | B110 Education | $509.3M | 9 |
| SAN ANTONIO REGIONAL HOSPITAL | Upland | E220 Health Care | $506.1M | 13 |
| THE J PAUL GETTY TRUST | Los Angeles | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $505.6M | 13 |
| REDWOOD CREDIT UNION | Santa Rosa | — | $504M | 22 |
| CENTER FOR SUSTAINABLE ENERGY | San Diego | C350 Environment | $502.9M | 8 |
| Hanford Community Hospital dba Adventist Health Hanford | Hanford | E220 Health Care | $497.9M | 26 |
| Rideout Memorial Hospital | Marysville | E220 Health Care | $491.9M | 24 |
| NORTH BAY DEVELOPMENTAL DISABILITIES SERVICES INC | Napa | P820 Human Services | $482.5M | 7 |
| THE MAXWELLHANRAHAN FOUNDATION | San Francisco | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $481.4M | 0 |
| CARPENTERS HEALTH AND WELFARE TRUST FUND FOR NORTHERN CALIFORNIA | Oakland | — | $479.7M | 9 |
| ELECTRIC POWER RESEARCH INSTITUTE INC | Palo Alto | W050 Public & Societal Benefit | $478.7M | 24 |
| San GabrielPomona Valleys Developmental Services Inc | Pomona | — | $478.6M | 12 |
| The Rand Corporation | Santa Monica | W050 Public & Societal Benefit | $461.5M | 25 |
| USC CARE MEDICAL GROUP INC | Los Angeles | E300 Health Care | $459.1M | 36 |
| CALIFORNIA BAPTIST UNIVERSITY | Riverside | B420 Education | $456.8M | 7 |
| COASTAL DEVELOPMENTAL SERVICES FOUNDATION | Culver City | — | $456.4M | 6 |
