| White Memorial Medical Center | Los Angeles | E220 Health Care | $650.2M | 23 |
| THE SCRIPPS RESEARCH INSTITUTE | La Jolla | H92 Medical Research | $641.1M | 15 |
| UNITED FOOD AND COMMERCIAL WORKERS | Cypress | — | $640.9M | 7 |
| South Central Los Angeles Regional | Los Angeles | P82Z Human Services | $637M | 10 |
| SAINT AGNES MEDICAL CENTER | Fresno | E220 Health Care | $624.8M | 14 |
| PRESIDENT-BOARD OF TRUSTEES | Santa Clara | B430 Education | $622M | 18 |
| San Joaquin Community Hospital | Bakersfield | E220 Health Care | $621.3M | 22 |
| BAKERSFIELD MEMORIAL HOSPITAL | San Francisco | E220 Health Care | $620.6M | 15 |
| PAC-12 CONFERENCE | San Ramon | N60Z Recreation & Sports | $603.9M | 28 |
| THE WILLIAM & FLORA HEWLETT FOUNDATION | Menlo Park | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $602.1M | 3 |
| Glendale Adventist Medical Center | Glendale | E220 Health Care | $586.2M | 21 |
| JOHN MUIR PHYSICIAN NETWORK | Walnut Creek | E32Z Health Care | $582M | 11 |
| EMANATE HEALTH MEDICAL CENTER | Covina | E220 Health Care | $579.6M | 7 |
| REGIONAL CENTER OF ORANGE COUNTY INC | Santa Ana | P820 Human Services | $558.2M | 7 |
| UNIVERSITY OF SAN DIEGO | San Diego | — | $554.5M | 28 |
| University of San Francisco | San Francisco | B430 Education | $553M | 18 |
| UNIVERSITY OF CALIFORNIA BERKELEY | Berkeley | B110 Education | $551.2M | 8 |
| TRI-COUNTIES ASSOCIATION FOR THE | Santa Barbara | — | $544.3M | 7 |
| EASTER SEALS SOUTHERN CALIFORNIA INC | Irvine | — | $535.5M | 8 |
| STANFORD HEALTH CARE TRI-VALLEY | Livermore | E200 Health Care | $531.8M | 23 |
| UFCW & EMPLOYERS BENEFIT TRUST | Concord | — | $529M | 7 |
| PATELCO CREDIT UNION | Dublin | — | $527.5M | 14 |
| JOINT BOARD OF TRUSTEES SOUTHWEST | Los Angeles | — | $526.2M | 7 |
| Central Valley Regional Center | Fresno | P820 Human Services | $522.4M | 7 |
| CENTRO DE SALUD DE LA COMUNIDAD DE | San Ysidro | E32Z Health Care | $521.8M | 18 |
| VALLEY PRESBYTERIAN HOSPITAL | Van Nuys | E220 Health Care | $517M | 22 |
| HENRY MAYO NEWHALL MEMORIAL HOSPITAL | Valencia | E220 Health Care | $512.2M | 15 |
| SAN ANTONIO REGIONAL HOSPITAL | Upland | E220 Health Care | $506.1M | 13 |
| REDWOOD CREDIT UNION | Santa Rosa | — | $504M | 22 |
| CENTER FOR SUSTAINABLE ENERGY | San Diego | C350 Environment | $502.9M | 8 |
| Hanford Community Hospital | Hanford | E220 Health Care | $497.9M | 26 |
| SUTTER VISITING NURSE ASSOCIATION | Sacramento | P74 Human Services | $491.9M | 19 |
| Rideout Memorial Hospital | Marysville | E220 Health Care | $491.9M | 24 |
| CHILD CARE RESOURCE CENTER INC | Chatsworth | O40Z Youth Development | $489.3M | 13 |
| University of the Pacific | Stockton | B430 Education | $488.7M | 31 |
| GOLDEN GATE REGIONAL CENTER INC | San Francisco | P820 Human Services | $485.1M | 5 |
| CARPENTERS HEALTH AND WELFARE TRUST | Oakland | — | $479.7M | 9 |
| ELECTRIC POWER RESEARCH INSTITUTE INC | Palo Alto | W050 Public & Societal Benefit | $478.7M | 24 |
| San GabrielPomona Valleys | Pomona | — | $478.6M | 12 |
| The Rand Corporation | Santa Monica | W050 Public & Societal Benefit | $467.2M | 26 |
| THE CARL VICTOR PAGE MEMORIAL FOUNDATION | Palo Alto | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $458.4M | 0 |
| COASTAL DEVELOPMENTAL SERVICES | Culver City | — | $456.4M | 6 |
| WILLIAM AND BARBARA MARTIN FOUNDATION | Los Angeles | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $455.3M | 0 |
| NORTHERN CALIFORNIA GENERAL TEAMSTERS | Stockton | — | $454.4M | 0 |
| SERGEY BRIN FAMILY FOUNDATION | San Francisco | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $453.7M | 0 |
| SAN DIEGO COUNTY CREDIT UNION | San Diego | — | $447.7M | 24 |
| LABORERS HEALTH & WELFARE TRUST FUND FOR | Pleasanton | — | $445.1M | 0 |
| CALIFORNIA BAPTIST UNIVERSITY | Riverside | B420 Education | $439.7M | 7 |
| SRI INTERNATIONAL | Menlo Park | U200 Science & Technology | $437.9M | 28 |
| Eastern Los Angeles Regional Center | Alhambra | P820 Human Services | $424.5M | 9 |
