| Eisenhower Medical Center | Rancho Mirage | E22 Health Care | $1.4B | 22 |
| Grossmont Hospital Corporation | San Diego | E220 Health Care | $1.1B | 17 |
| Santa Barbara Cottage Hospital | Santa Barbara | E220 Health Care | $1.1B | 9 |
| LOS ANGELES LOMOD CORPORATION | Los Angeles | — | $1.1B | 3 |
| Sharp Health Plan | San Diego | — | $1B | 16 |
| CAMP BOWIE SERVICE CENTER | Oakland | E02 Health Care | $1B | 20 |
| MOTION PICTURE INDUSTRY HEALTH PLAN | Studio City | — | $1B | 9 |
| INLAND COUNTIES REGIONAL CENTER INC | San Bernardino | P820 Human Services | $1B | 21 |
| FOSTER CHARITABLE TRUST | Marina Del Rey | — | $1B | 0 |
| ENLOE MEDICAL CENTER | Chico | E220 Health Care | $998M | 14 |
| THE GOLDEN 1 CREDIT UNION | Sacramento | W61 Public & Societal Benefit | $989.7M | 26 |
| CALIFORNIA SCHOOLS VOL EMP BEN ASSOC FKA SOCAL SCHOOLS VOL EMP BENEFITS AS | San Diego | — | $989.3M | 0 |
| ILWU-PMA WELFARE TRUST | San Francisco | — | $974M | 6 |
| LOKAHI ASSURANCE LTD | Oakland | Y200 Mutual & Membership Benefit | $967.5M | 9 |
| VALLEY CHILDREN'S HOSPITAL | Madera | E240 Health Care | $966.4M | 23 |
| PIH Health Whittier Hospital | Whittier | E220 Health Care | $962.4M | 30 |
| NORTH LOS ANGELES COUNTY REGIONAL CENTER INC | Chatsworth | — | $953.9M | 11 |
| Torrance Memorial Medical Center | Torrance | E220 Health Care | $932.7M | 15 |
| COMMUNITY HOSPITAL OF THE MONTEREY PENINSULA | Monterey | E220 Health Care | $919.6M | 16 |
| CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | Oakland | E240 Health Care | $905.4M | 17 |
| H&H EVERGREEN FOUNDATION | Menlo Park | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $902.2M | 1 |
| Pasadena Hospital Association Ltd | Pasadena | E220 Health Care | $891M | 25 |
| Adventist Health SystemWest | Roseville | E210 Health Care | $890.3M | 47 |
| Pomona Valley Hospital Medical Center | Pomona | E220 Health Care | $889.8M | 13 |
| PORT CITY OPERATING COMPANY LLC | Rancho Cordova | E20 Health Care | $878.6M | 7 |
| PHARMACY4HUMANITY | Los Angeles | P80 Human Services | $878.4M | 20 |
| CEDARS-SINAI MEDICAL CARE FOUNDATION | Los Angeles | E110 Health Care | $865.2M | 14 |
| NORTHBAY HEALTHCARE GROUP | Fairfield | E210 Health Care | $850.1M | 22 |
| California's Valued Trust | Fresno | — | $846.8M | 15 |
| SUTTER HEALTH ALLIANCE (FKA SUTTER HEALTH PLAN) | Sacramento | E31 Health Care | $837.8M | 14 |
| Regional Center of the East Bay Inc | San Leandro | P820 Human Services | $832.2M | 7 |
| SAN DIEGO IMPERIAL COUNTIES DEVELOPMENTAL SERVICES INC | San Diego | P820 Human Services | $820.8M | 7 |
| WESTERN HEALTH ADVANTAGE | Sacramento | E31 Health Care | $806.4M | 12 |
| ALTA CALIFORNIA REGIONAL CENTER INC | Sacramento | — | $799.6M | 11 |
| THE CARL VICTOR PAGE MEMORIAL FOUNDATION | Palo Alto | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $798.6M | 0 |
| CITY OF HOPE MEDICAL FOUNDATION | Duarte | E32 Health Care | $789.3M | 17 |
| THE WILLIAM & FLORA HEWLETT FOUNDATION | Menlo Park | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $784.7M | 6 |
| PRIME HEALTHCARE FOUNDATION INC | Ontario | E20 Health Care | $776.3M | 44 |
| CHAPMAN UNIVERSITY | Orange | B430 Education | $776.2M | 16 |
| SAN ANDREAS REGIONAL CENTER | San Jose | P820 Human Services | $758.1M | 10 |
| BAKERSFIELD MEMORIAL HOSPITAL | San Francisco | E220 Health Care | $744.2M | 15 |
| REGIONAL CENTER OF ORANGE COUNTY INC | Santa Ana | P820 Human Services | $724.3M | 8 |
| UCLA FOUNDATION | Los Angeles | B110 Education | $722.5M | 6 |
| Faculty Physicians & Surgeons of LLUSM | Loma Linda | E120 Health Care | $720.5M | 39 |
| SCRIPPS HEALTH PLAN SERVICES INC | San Diego | E31 Health Care | $706.5M | 11 |
| PEPPERDINE UNIVERSITY | Malibu | B430 Education | $705.5M | 34 |
| CATALYST4 INC | Palo Alto | C01 Environment | $700.8M | 0 |
| LOMA LINDA UNIVERSITY CHILDREN'S HOSPITAL | Loma Linda | — | $700M | 34 |
| LOYOLA MARYMOUNT UNIVERSITY | Los Angeles | B43 Education | $697.6M | 20 |
| White Memorial Medical Center dba Adventist Health White Memorial | Los Angeles | E220 Health Care | $689.6M | 23 |
