| Herman Miller Inc Benefits Trust | Zeeland | — | $40M | 1 |
| HEGIRA HEALTH INC | Livonia | F22Z Mental Health & Crisis Intervention | $39.7M | 10 |
| CARE RESOURCES | Grand Rapids | E99 Health Care | $39.7M | 0 |
| Center for Family Health | Jackson | E30Z Health Care | $39.6M | 11 |
| INTERCARE COMMUNITY HEALTH NETWORK | Bangor | F302 Mental Health & Crisis Intervention | $39.6M | 9 |
| DTE ENERGY COMPANY MASTER VEBA TRUST | Detroit | Y43 Mutual & Membership Benefit | $39.2M | 1 |
| MICHIGAN EDUCATIONAL CREDIT UNION | Plymouth | — | $39M | 11 |
| THE SENIOR ALLIANCE INC | Dearborn | P81Z Human Services | $38.9M | 4 |
| DETROIT RIVERFRONT CONSERVANCY INC | Detroit | N32 Recreation & Sports | $38.9M | 7 |
| Hackley Community Care Center Inc | Muskegon | — | $38.8M | 12 |
| TRINITY HEALTH LIFE PENNSYLVANIA INC | Livonia | — | $38.7M | 13 |
| THE GILBERT FAMILY FOUNDATION | Detroit | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $38.5M | 0 |
| GRAND RAPIDS CHRISTIAN SCHOOLS | Grand Rapids | B21Z Education | $38.3M | 5 |
| SPECTRUM COMMUNITY SERVICES | Westland | P73Z Human Services | $37.6M | 5 |
| JOHN BALL ZOO | Grand Rapids | D115 Animal-Related | $37.3M | 7 |
| UPCAP SERVICES INC | Escanaba | P120 Human Services | $37.3M | 1 |
| KALAMAZOO PROMISE | Kalamazoo | B82 Education | $37.3M | 0 |
| HURON VALLEY AMBULANCE | Ann Arbor | E62Z Health Care | $37M | 1 |
| Resthaven | Holland | — | $36.7M | 7 |
| GOODWILL INDUSTRIES OF MID-MICHIGAN INC | Flint | J32Z Employment | $36.7M | 4 |
| Sunset Hills Association | Flint | — | $36.5M | 5 |
| SOUTHEAST MICHIGAN COMMUNITY ALLIANCE | Taylor | P20 Human Services | $36.4M | 11 |
| VISTA MARIA | Dearborn Heights | — | $36.3M | 10 |
| MICHIGAN STATE AFL-CIO WORKFORCE DEVELOPMENT INSTITUTE | Lansing | J200 Employment | $36.3M | 4 |
| THUNDER BAY COMMUNITY HEALTH SERVIC | Hillman | E39Z Health Care | $36.2M | 9 |
| ST JOSEPH OF THE PINES INC | Livonia | — | $36M | 9 |
| LUTHERAN HOMES OF MICHIGAN INC | Saginaw | E910 Health Care | $36M | 9 |
| CSI SUPPORT & DEVELOPMENT SERVICES | Warren | L02 Housing & Shelter | $35.9M | 7 |
| LABORERS METROPOLITAN DETROIT HEALTH CARE FUND | Lansing | — | $35.9M | 6 |
| MEDICAL CENTER EMERGENCY SERVICES | Detroit | E300 Health Care | $35.5M | 21 |
| COVENANT MISSIONS | Roseville | — | $35.2M | 0 |
| FOCUSHOPE | Detroit | P200 Human Services | $35.1M | 6 |
| Thumb Electric Cooperative of Michigan | Ubly | — | $34.6M | 17 |
| GRAND TRAVERSE REGIONAL LAND CONSERVANCY | Traverse City | C340 Environment | $34.5M | 6 |
| SUNSET MANOR INC | Jenison | P750 Human Services | $34.4M | 7 |
| Eversight | Ann Arbor | — | $34M | 11 |
| THE RIGHT PLACE INC | Grand Rapids | — | $33.9M | 7 |
| SOUTHEASTERN MI HEALTH ASSOCIATION | Detroit | — | $33.8M | 7 |
| GOODWILL INDUSTRIES OF CENTRAL MICHIGAN'S HEARTLAND INC | Battle Creek | J32Z Employment | $33.7M | 5 |
| WORLD MEDICAL RELIEF INCORPORATED | Southfield | Q300 International, Foreign Affairs & National Security | $33.4M | 1 |
| HAMILTON COMMUNITY HEALTH NETWORK INC | Flint | E320 Health Care | $33.4M | 10 |
| Senior Resources of West Michigan | Muskegon | P81Z Human Services | $33.4M | 4 |
| SHERIDAN COMMUNITY HOSPITAL | Sheridan | E22 Health Care | $33.2M | 10 |
| THOMAS M COOLEY LAW SCHOOL | Lansing | B500 Education | $33.1M | 14 |
| Human Development Fund | Canton | Q33 International, Foreign Affairs & National Security | $33M | 1 |
| MCKENZIE MEMORIAL HOSPITAL MCKENZIE HEALTH SYSTEM | Sandusky | E22Z Health Care | $32.9M | 13 |
| ALTARUM INSTITUTE | Novi | U050 Science & Technology | $32.8M | 25 |
| WEST MICHIGAN HORTICULTURAL SOCIETY INC DBA FREDERIK MEIJER GARDENS | Grand Rapids | C420 Environment | $32.8M | 9 |
| MICHIGAN REGIONAL COUNCIL OF CARPENTERS | Detroit | — | $32.5M | 16 |
| Michigan Family Resources | Grand Rapids | B22Z Education | $31.7M | 11 |
