| RUSSELL SAGE COLLEGE | Troy | B420 Education | $75.8M | 11 |
| NAACP LEGAL DEFENSE & EDUC FUND INC | New York | R220 Civil Rights, Social Action & Advocacy | $75.7M | 12 |
| HELEN KELLER INTERNATIONAL | New York | Q300 International, Foreign Affairs & National Security | $75.7M | 17 |
| CORPORATION FOR SUPPORTIVE HOUSING | New York | L210 Housing & Shelter | $75.3M | 8 |
| JEWISH COMMUNITY COUNCIL OF GREATER CONEY ISLAND INC | Brooklyn | P200 Human Services | $75.3M | 8 |
| ST ANN'S HOME FOR THE AGED | Rochester | E910 Health Care | $75.1M | 13 |
| COMUNILIFE INC | New York | Z99Z Unknown | $75M | 8 |
| EQUITY-LEAGUE HEALTH TRUST FUND | New York | — | $75M | 6 |
| INT'L SWAPS & DERIVATIVES ASSOCIATION INC | New York | — | $74.6M | 11 |
| THE NHP FOUNDATION | New York | L200 Housing & Shelter | $74.5M | 13 |
| BIRTHRIGHT ISRAEL FOUNDATION | New York | Q230 International, Foreign Affairs & National Security | $74.3M | 13 |
| REHABILITATION SUPPORT SERVICES INC | Altamont | F330 Mental Health & Crisis Intervention | $74.2M | 11 |
| MASSENA HOSPITAL INC | Massena | E22 Health Care | $74.1M | 13 |
| AMERICANS FOR BEN-GURION UNIVERSITY INC | New York | B110 Education | $74M | 7 |
| NEW YORK PUBLIC RADIO | New York | A340 Arts, Culture & Humanities | $73.9M | 12 |
| MARY MANNING WALSH NURSING HOME CO INC | New York | E910 Health Care | $73.8M | 8 |
| LORETTO HEALTH & REHABILITATION CENTER | Syracuse | E91 Health Care | $73.7M | 9 |
| PACKER COLLEGIATE INSTITUTE | Brooklyn | B200 Education | $73.7M | 16 |
| C40 Cities Climate Leadership Group Inc | New York | C029 Environment | $73.6M | 8 |
| HIGHLAND PARK COMMUNITY DEVELOPMENT CORPORATION | Brooklyn | L80 Housing & Shelter | $73.6M | 14 |
| TOURO UNIVERSITY NEVADA | New York | B50 Education | $73.6M | 16 |
| ZETA CHARTER SCHOOLS - NEW YORK CITY | Bronx | B29 Education | $73.5M | 10 |
| CORNERSTONE FAMILY HEALTHCARE FKA GREATER HUDSON VALLEY HEALTH CENTER | Cornwall | E32Z Health Care | $73.4M | 10 |
| NEW HORIZON COUNSELING CENTER INC | Ozone Park | — | $73.2M | 19 |
| SUNNYVIEW HOSPITAL AND REHABILITATION CENTER | Schenectady | E240 Health Care | $73.2M | 16 |
| OPEN SPACE INSTITUTE LAND TRUST INC | New York | C340 Environment | $73.1M | 19 |
| UFCW LOCAL ONE HEALTH CARE FUND | Oriskany | Y43 Mutual & Membership Benefit | $73.1M | 7 |
| 1199 SEIU LEAGUE TRAINING AND UPGRADING FUND | New York | J200 Employment | $72.9M | 9 |
| CFCU COMMUNITY CREDIT UNION | Ithaca | — | $72.9M | 11 |
| CHAUTAUQUA COUNTY CHAPTER OF NYSARC INC | Jamestown | P82Z Human Services | $72.9M | 8 |
| MARYHAVEN CENTER OF HOPE INC | Manorville | — | $72.7M | 11 |
| SAINT DOMINIC'S FAMILY SERVICES (FORMERLY SAINT DOMINIC'S HOME) | Blauvelt | — | $72.4M | 7 |
| NYSARC INC - SUFFOLK CHAPTER | Bohemia | P820 Human Services | $72.4M | 8 |
| FOODLINK INC | Rochester | K30 Food, Agriculture & Nutrition | $72.3M | 8 |
| CARDINAL MCCLOSKEY SCHOOL AND HOME FOR CHILDREN | Valhalla | — | $72M | 8 |
| NEW YORK EDGE INC | Woodside | N20Z Recreation & Sports | $71.9M | 5 |
| NEW HOPE COMMUNITY INC | Loch Sheldrake | P700 Human Services | $71.7M | 9 |
| YMCA OF GREATER ROCHESTER (4368) | Rochester | P270 Human Services | $71.6M | 6 |
| OZANAM HALL OF QUEENS NURSING HOME INC | Bayside | E91 Health Care | $71.6M | 6 |
| WILLIAM F RYAN COMMUNITY HEALTH CENTER INC | New York | E320 Health Care | $71.6M | 12 |
| UNIVERSITY ORTHOPAEDIC SERVICES INC | Cheektowaga | E31Z Health Care | $71.5M | 37 |
| Steamfitters Industry Welfare Fund | Long Island City | J40 Employment | $71.4M | 9 |
| COMMON GROUND MANAGEMENT CORP | New York | J20 Employment | $71.3M | 10 |
| AFRICAN AMERICAN PLANNING COMMISSION INC | Brooklyn | P20 Human Services | $71.3M | 4 |
| THE JONATHAN M TISCH FAMILY FOUNDATION | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $71.3M | 0 |
| NATIONAL SOCIETY FOR HEBREW DAY SCHOOLS | Brooklyn | X300 Religion-Related | $71.1M | 6 |
| NEW YORK ATHLETIC CLUB | New York | — | $70.9M | 8 |
| COLUMBIADOCTORSNEWYORK-PRESBYTERIAN IMAGING | New York | E21 Health Care | $70.8M | 0 |
| TRILLIUM HEALTH INC | Rochester | — | $70.6M | 10 |
| THE SCHULMAN AND SCHACHNE INSTITUTE FOR NURSING AND REHABILITATION INC | Brooklyn | E910 Health Care | $70.6M | 12 |
