| FREEDOM TOGETHER FOUNDATION | New York | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $1.1B | 11 |
| Fordham University | Bronx | B430 Education | $1.1B | 23 |
| BROOKDALE HOSPITAL MEDICAL CENTER | Brooklyn | E220 Health Care | $1.1B | 18 |
| Physician Affiliate Group of New York PC | New York | E20 Health Care | $1.1B | 36 |
| WORLD FEDERATION OF HEMOPHILIA USA | Albany | G20 Diseases, Disorders & Medical Disciplines | $1.1B | 0 |
| HEALTH RESEARCH INC | Menands | H300 Medical Research | $1.1B | 9 |
| NEWYORK-PRESBYTERIANQUEENS | Flushing | E22 Health Care | $1.1B | 24 |
| BETH ISRAEL MEDICAL CENTER | New York | E220 Health Care | $1.1B | 23 |
| IBM Medical Benefits Trust | Brooklyn | — | $1.1B | 1 |
| THE ANDREW W MELLON FOUNDATION | New York | B82 Education | $1.1B | 17 |
| White Plains Hospital Medical Center | White Plains | E220 Health Care | $1B | 12 |
| JPMORGAN CHASE FOUNDATION | New York | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $995.5M | 0 |
| ST FRANCIS HOSPITAL | Roslyn | E220 Health Care | $960.2M | 12 |
| BronxCare Health Systems | Bronx | E220 Health Care | $950.1M | 13 |
| Vassar Brothers Medical Center | Poughkeepsie | E220 Health Care | $904.3M | 14 |
| NORTHWELL HEALTH LABORATORIES | Westbury | E60 Health Care | $872.2M | 15 |
| GOOD SAMARITAN HOSPITAL MEDICAL CENTER | West Islip | E220 Health Care | $857.8M | 10 |
| MANAGEMENT-ILA MANAGED HEALTH CARE TRUST FUND | New York | — | $844.4M | 2 |
| FOUNDATION TO PROMOTE OPEN SOCIETY | New York | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $842.8M | 0 |
| JAMAICA HOSPITAL MEDICAL CENTER | Jamaica | E220 Health Care | $840.7M | 9 |
| ST PETER'S HOSPITAL | Albany | E220 Health Care | $810.1M | 16 |
| ST JOHN'S UNIVERSITY NEW YORK | Jamaica | B430 Education | $799.6M | 9 |
| MEDECINS SANS FRONTIERES USA INC | New York | Q300 International, Foreign Affairs & National Security | $776.9M | 26 |
| NYC SCHOOL SUPPORT SERVICES INC | New York | B11 Education | $767.4M | 7 |
| SOUTH NASSAU COMMUNITIES HOSPITAL INC | Oceanside | E22 Health Care | $760.6M | 15 |
| S&G FOUNDATION INC | Albany | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $744M | 0 |
| MANHATTAN AND BRONX SURFACE TRANSIT OPERATING AUTHORITY | New York | — | $736.1M | 5 |
| PLAN INTERNATIONAL INC | New York | Q330 International, Foreign Affairs & National Security | $726.9M | 25 |
| Huntington Hospital Association C/O NORTHWELL HEALTH INC | Westbury | E220 Health Care | $722.9M | 9 |
| UNITED STATES FUND FOR UNICEF | New York | Q420 International, Foreign Affairs & National Security | $720.4M | 14 |
| THE UNITY HOSPITAL OF ROCHESTER | Rochester | E220 Health Care | $717.2M | 17 |
| Rensselaer Polytechnic Institute | Troy | B430 Education | $709.4M | 24 |
| PACE UNIVERSITY | New York | B40 Education | $707.7M | 36 |
| ROCKEFELLER PHILANTHROPY ADVISORS INC | New York | T500 Philanthropy, Voluntarism & Grantmaking Foundations | $706M | 17 |
| HOFSTRA UNIVERSITY | Hempstead | B430 Education | $705.8M | 16 |
| THE JEWISH FEDERATIONS OF NORTH AMERICA INC | New York | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $702.4M | 14 |
| METROPOLITAN MUSEUM OF ART | New York | A510 Arts, Culture & Humanities | $697.6M | 18 |
| THE MARY IMOGENE BASSETT HOSPITAL | Cooperstown | E220 Health Care | $694.5M | 8 |
| Research Foundation of the City University of New York | New York | B110 Education | $673M | 14 |
| Garnet Health Medical Center | Middletown | E220 Health Care | $664.2M | 9 |
| CENTERLIGHT HEALTHCARE INC | Flushing | E210 Health Care | $660.2M | 11 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION RETIREMENT FUND | New York | Y300 Mutual & Membership Benefit | $649.3M | 14 |
| ST JOSEPH'S HOSPITAL HEALTH CENTER | Syracuse | E220 Health Care | $622.1M | 18 |
| NEW YORK BLOOD CENTER INC | Rye | E610 Health Care | $605.8M | 30 |
| BON SECOURS CHARITY HEALTH SYSTEM AFFILIATED GROUP | Suffern | E21 Health Care | $603.7M | 11 |
| ST BARNABAS HOSPITAL | Bronx | E20 Health Care | $603.3M | 11 |
| BAR ILAN UNIVERSITY IN ISRAEL INC | New York | — | $603.1M | 10 |
| NORTHERN WESTCHESTER HOSPITAL ASSOCIATION C/O NORTHWELL HEALTH INC | Westbury | E220 Health Care | $594M | 18 |
| The New School | New York | B430 Education | $588.1M | 29 |
| NEW YORK STATE NURSES ASSOCIATION BENEFITS FUND | Albany | Y43 Mutual & Membership Benefit | $584.7M | 5 |
