| COORDINATED TRANSPORTATION | Trumbull | P52 Human Services | $152M | 5 |
| UFCW AND PARTICIPATING EMPLOYERS NEW | Westport | — | $151.9M | 6 |
| Hartford HealthCare at Home Inc | Wethersfield | E920 Health Care | $147.4M | 14 |
| ALEXION ACCESS FOUNDATION | New Haven | E60 Health Care | $144.8M | 0 |
| STEVEN & ALEXANDRA COHEN FOUNDATION INC | Stamford | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $138.2M | 0 |
| Hospital For Special Care | New Britain | E240 Health Care | $136M | 18 |
| LMW HEALTHCARE INC | New London | E22 Health Care | $135.6M | 8 |
| Day Kimball Healthcare Inc | Putnam | E220 Health Care | $128.7M | 13 |
| THE UNIVERSITY OF BRIDGEPORT INC | Bridgeport | B43 Education | $127.2M | 11 |
| AMERICAN EAGLE FINANCIAL CREDIT UNION | East Hartford | W61 Public & Societal Benefit | $127.1M | 23 |
| TRI-STATE JOINT FUND | Cheshire | — | $124.3M | 4 |
| Windham Community Memorial Hospital Inc | Willimantic | E220 Health Care | $122.4M | 17 |
| CONNECTICUT FOODSHARE INC | Wallingford | — | $120.2M | 7 |
| CW RESOURCES INC | New Britain | J220 Employment | $114.8M | 12 |
| NEW ENGLAND ELECTRICAL WORKERS | Meriden | — | $106.3M | 4 |
| Gaylord Hospital INC | Wallingford | E240 Health Care | $102.5M | 14 |
| CORNELL SCOTT-HILL HEALTH CORPORATION | New Haven | E320 Health Care | $100.1M | 12 |
| THE BERKLEY FOUNDATION FOR HISTORICAL | Greenwich | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $100M | 0 |
| WHEELER CLINIC INC | Plainville | F200 Mental Health & Crisis Intervention | $98.5M | 10 |
| THE UNIVERSITY OF CONNECTICUT FOUNDATION | Storrs | B110 Education | $97.5M | 10 |
| THE ZOOM FOUNDATION | Greenwich | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $97.3M | 0 |
| THE CONNECTICUT INSTITUTE FOR THE | Hartford | P860 Human Services | $93.5M | 8 |
| Hartford HealthCare Endowment LLC | Hartford | — | $92.6M | 8 |
| GREENWICH COUNTRY DAY SCHOOL INC | Greenwich | B240 Education | $91.9M | 7 |
| THE HOTCHKISS SCHOOL | Lakeville | B250 Education | $88.8M | 9 |
| CHOATE ROSEMARY HALL FOUNDATION | Wallingford | B250 Education | $87.9M | 8 |
| UNIVERSITY OF SAINT JOSEPH | West Hartford | B430 Education | $86.5M | 8 |
| KNIGHTS OF COLUMBUS CHARITABLE FUND INC | New Haven | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $85.5M | 0 |
| COMMUNITY HEALTH NETWORK OF | Wallingford | E21 Health Care | $84.1M | 18 |
| Stamford Health Pharmacy LLC | Stamford | E6A Health Care | $81.9M | 1 |
| FINANCIAL ACCOUNTING FOUNDATION | Norwalk | W190 Public & Societal Benefit | $80.8M | 27 |
| THE LOOMIS INSTITUTE | Windsor | B250 Education | $80.7M | 8 |
| THE TAFT SCHOOL CORPORATION | Watertown | B250 Education | $80.4M | 11 |
| BRUNSWICK SCHOOL INC | Greenwich | B200 Education | $77M | 8 |
| FOOD RESCUE US INC | Stamford | K40 Food, Agriculture & Nutrition | $75.1M | 1 |
| RIVERBEND MEDICAL GROUP INC | Hartford | E32 Health Care | $75M | 12 |
| JOHNSON MEMORIAL HOSPITAL INC | Hartford | E22 Health Care | $74.6M | 18 |
| JEWISH HOME FOR THE ELDERLY OF FAIRFIELD | Bridgeport | E910 Health Care | $74.4M | 10 |
| CONNECTICUT STATE EMPLOYEES CREDIT UNION INC | Hartford | — | $74.3M | 6 |
| COMMUNITY HEALTH RESOURCES INC | Windsor | F30 Mental Health & Crisis Intervention | $73.1M | 11 |
| CAPITAL AREA HEALTH CONSORTIUM INC | Farmington | — | $68.3M | 17 |
| INTERNATIONAL UNION OF OPERATING | Hamden | — | $67.4M | 6 |
| HARTFORD FOUNDATION FOR PUBLIC GIVING | Hartford | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $67.4M | 8 |
| GOODWIN UNIVERSITY INC | East Hartford | B42 Education | $65.6M | 8 |
| SILVER HILL HOSPITAL INC | New Canaan | F310 Mental Health & Crisis Intervention | $64M | 15 |
| Ability Beyond Disability Inc | Bethel | P800 Human Services | $63.4M | 7 |
| Raytheon Welfare Benefits Trust | Farmington | Y43 Mutual & Membership Benefit | $62.9M | 1 |
| SEEDLINGS FOUNDATION | Branford | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $62.6M | 0 |
| KENT SCHOOL | Kent | B250 Education | $62.4M | 8 |
| CONNECTICUT LABORERS' HEALTH FUND | West Haven | — | $61.6M | 9 |
