| TI EMPLOYEES HEALTH BENEFIT TRUST | Dallas | — | $194M | 1 |
| COMPASS CONNECTIONS | San Antonio | P30 Human Services | $192.3M | 3 |
| SOUTH PLAINS ELECTRIC COOPERATIVE INC | Lubbock | — | $191.2M | 21 |
| AUSTIN TRANSIT PARTNERSHIP | Austin | W40 Public & Societal Benefit | $188.2M | 12 |
| ST DAVID'S FOUNDATION | Austin | E210 Health Care | $187.7M | 13 |
| CREDIT UNION OF TEXAS | Allen | — | $187.6M | 26 |
| Dallas County Local Workforce Development Board | Dallas | P800 Human Services | $185.8M | 7 |
| SAN MIGUEL ELECTRIC COOPERATIVE INC | Jourdanton | — | $185M | 27 |
| FIRST CHOICE PHYSICIAN PARTNERS | Dallas | E30 Health Care | $184.5M | 5 |
| The Brown Foundation Inc | Houston | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $183.8M | 0 |
| SOUTHWESTERN MEDICAL FOUNDATION | Dallas | B110 Education | $183.1M | 8 |
| ST EDWARDS UNIVERSITY | Austin | B430 Education | $181.7M | 15 |
| BRAZOS SANDY CREEK ELECTRIC COOPERATIVE INC | Houston | — | $180.7M | 0 |
| St Mary's University | San Antonio | — | $180.3M | 23 |
| Texas Health Hospital Frisco | Frisco | E20 Health Care | $172.3M | 18 |
| THE PROFESSIONAL GOLFERS ASSOC | Frisco | — | $172.3M | 12 |
| Adventist Health SystemTexas Inc | Burleson | — | $171.2M | 10 |
| ALAMO WORKFORCE DEVELOPMENT INC | San Antonio | J200 Employment | $171.2M | 5 |
| SAN ANTONIO FOOD BANK | San Antonio | — | $169.1M | 6 |
| PROFESSIONAL CONTRACT SERVICES INC | Austin | P80Z Human Services | $166.5M | 18 |
| THE ROSE FAMILY FOUNDATION | Dallas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $166.4M | 0 |
| MEMORIAL HEALTH SYSTEM OF EAST TEXAS | Lufkin | E220 Health Care | $166.2M | 15 |
| Young Men's Christian Association of the Greater Houston Area | Houston | P270 Human Services | $165.8M | 10 |
| The Moody Foundation | Galveston | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $162.8M | 3 |
| MEDINA ELECTRIC COOPERATIVE INC | Hondo | — | $160.6M | 21 |
| HOUSTON CHRISTIAN UNIVERSITY | Houston | — | $158.2M | 13 |
| MISSION HOSPITAL INC | Mission | E220 Health Care | $157.7M | 11 |
| CARL & MARILYNN THOMA FOUNDATION | Dallas | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $156.8M | 0 |
| MedHealth | Dallas | E30 Health Care | $153.9M | 33 |
| Catholic Life Insurance | San Antonio | — | $152.8M | 17 |
| MID-SOUTH ELECTRIC COOPERATIVE | Navasota | — | $151.2M | 18 |
| DALLAS BAPTIST UNIVERSITY | Dallas | B430 Education | $150M | 19 |
| THE MUSEUM OF FINE ARTS HOUSTON | Houston | A510 Arts, Culture & Humanities | $148M | 11 |
| CHILD CARE ASSOCIATES | Fort Worth | — | $147.7M | 15 |
| Scott & White Care Plans | Dallas | P20 Human Services | $147.4M | 6 |
| CARTER BLOODCARE | Bedford | E610 Health Care | $147.3M | 18 |
| SOUTHWESTERN UNIVERSITY | Georgetown | B420 Education | $146.3M | 11 |
| FIRST COMMUNITY CREDIT UNION | Houston | — | $143.5M | 26 |
| C2C INNOVATIVE SOLUTIONS INC | Austin | E19 Health Care | $143.4M | 19 |
| THE 85 FUND | Fort Worth | I01 Crime & Legal-Related | $143.1M | 6 |
| RIVERWALK EDUCATION FOUNDATION INC | San Antonio | B29 Education | $141.9M | 31 |
| Century Integrated Partners Inc | Dallas | E32 Health Care | $141.9M | 8 |
| Active Employees MedicalDental and Life Insurance Plan(s) for Employees of | Dallas | — | $141.5M | 0 |
| CENTRAL TEXAS FOOD BANK INC | Austin | K31Z Food, Agriculture & Nutrition | $141.4M | 10 |
| AUSTIN TRAVIS COUNTY MHMR CENTER | Austin | F320 Mental Health & Crisis Intervention | $141.3M | 10 |
| UNIVERSITY OF MARY HARDIN-BAYLOR | Belton | B430 Education | $138.6M | 9 |
| Baylor Scott & White Medical Center - | Dallas | E22 Health Care | $137.3M | 14 |
| Christus Hopkins Health Alliance | Irving | — | $137.3M | 17 |
| THE SEALY & SMITH FOUNDATION | Galveston | E110 Health Care | $135.7M | 9 |
| Texas Health Presbyterian Hospital Allen | Allen | E220 Health Care | $135.7M | 20 |
