| CORNING INCORPORATED LONG TERM DISABILITY | Pittsburgh | — | $90.5M | 1 |
| MERCY LIFE | Philadelphia | E220 Health Care | $90.3M | 17 |
| THE BANK OF NEW YORK MELLON CORPORATION | Pittsburgh | Y24 Mutual & Membership Benefit | $90.1M | 0 |
| TRINITY HEALTH OF THE MID-ATLANTIC REGION | Newtown Square | E210 Health Care | $89.4M | 12 |
| MARIS GROVE INC | Glen Mills | L22 Housing & Shelter | $89.4M | 8 |
| PITTSBURGH CARE PARTNERSHIP INC | Pittsburgh | E91 Health Care | $89.4M | 7 |
| J HOWARD PEW FREEDOM TRUST | Philadelphia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $89.1M | 1 |
| THE PHILADELPHIA FOUNDATION | Philadelphia | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $88.9M | 8 |
| THE KARABOTS FOUNDATION | Fort Washington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $88.4M | 0 |
| HUMANGOOD PENNSYLVANIA | Lafayette Hill | P750 Human Services | $88.3M | 22 |
| DIAKON | Topton | — | $87.9M | 9 |
| THE UNION LEAGUE OF PHILADELPHIA | Philadelphia | — | $87.3M | 16 |
| Hemophilia Center of Western PA | Pittsburgh | E30 Health Care | $87.1M | 7 |
| SPECIAL PEOPLE IN NORTHEAST INC | Philadelphia | P82Z Human Services | $86.9M | 18 |
| MASTERY SCHOOLS OF CAMDEN INC | Philadelphia | B28 Education | $86.8M | 5 |
| MILLCREEK COMMUNITY HOSPITAL | Erie | E220 Health Care | $86.2M | 13 |
| LINCOLN UNIVERSITY | Lincoln University | B430 Education | $86.1M | 14 |
| PASSAVANT MEMORIAL HOMES | Pittsburgh | P700 Human Services | $86.1M | 4 |
| PHILHAVEN | York | F310 Mental Health & Crisis Intervention | $85.8M | 17 |
| GREATER PITTSBURGH COMMUNITY FOOD BANK | Duquesne | K310 Food, Agriculture & Nutrition | $85.4M | 10 |
| RICHARD J CARON FOUNDATION | Wernersville | F200 Mental Health & Crisis Intervention | $85.4M | 14 |
| LYCOMING COLLEGE | Williamsport | B420 Education | $85.1M | 15 |
| PG&E Postretirement Medical Plan Trust Non- Management Employees and Retirees | Pittsburgh | — | $84.5M | 1 |
| PHILADELPHIA ORCHESTRA ASSOCIATION | Philadelphia | A690 Arts, Culture & Humanities | $84.4M | 10 |
| PENNSYLVANIA STATE EDUCATION ASSOCIATION | Harrisburg | — | $83.9M | 59 |
| PITTSBURGH CULTURAL TRUST | Pittsburgh | A200 Arts, Culture & Humanities | $83.8M | 9 |
| ADAMS ELECTRIC COOPERATIVE INC | Gettysburg | — | $83.5M | 17 |
| INSPIRITEC INC | Philadelphia | B99 Education | $83.3M | 8 |
| PMHCC INC | Philadelphia | F300 Mental Health & Crisis Intervention | $82.8M | 7 |
| ALLIED HEALTH CARE SERVICES | Clarks Summit | P73Z Human Services | $82.8M | 7 |
| TRUSTEES OF THE UNIV OF PENNA RETIREE MED & DEATH BENEFITS TRUST | Philadelphia | Y330 Mutual & Membership Benefit | $82.7M | 0 |
| MOUNTAIN VIEW CANCER ASSOCIATES INC | Pittsburgh | E20 Health Care | $82.6M | 0 |
| GOODWILL OF SOUTHWESTERN PENNSYLVANIA | Pittsburgh | J320 Employment | $82.3M | 9 |
| ARCHWAY CHARTER SCHOOL OF CHESTER CHARTER CHOICE INC | Chester | B24 Education | $81.5M | 9 |
| PHILADELPHIA MUSEUM OF ART | Philadelphia | A510 Arts, Culture & Humanities | $81.1M | 11 |
| J E BARBEY 8 FBO TENACRE FDN | Pittsburgh | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $81M | 3 |
| LANCASTER GENERAL HEALTH | Lancaster | E120 Health Care | $80.9M | 33 |
| EMERGENCY CARE RESEARCH INSTITUTE | Doylestown | E64E Health Care | $80.4M | 21 |
| MERAKEY USA | Lafayette Hill | E21 Health Care | $80.4M | 13 |
| ST JOSEPH MEDICAL GROUP | Hershey | E32 Health Care | $80.2M | 12 |
| JEVS HUMAN SERVICES | Philadelphia | — | $80.1M | 23 |
| GEISINGER-BLOOMSBURG HOSPITAL | Danville | E20 Health Care | $79.9M | 14 |
| LYCOMING CLINTON JOINDER BOARD | Williamsport | P82Z Human Services | $79.7M | 2 |
| FREEDOM CREDIT UNION | Warminster | — | $79.7M | 16 |
| TRUST FOR GTE BARGAINED RETIRED GROUP INSURANCE | Pittsburgh | — | $79M | 1 |
| GOOD SHEPHERD REHABILITATION NETWORK | Allentown | E120 Health Care | $78.9M | 13 |
| HARRISBURG UNIVERSITY OF SCIENCE AND TECHNOLOGY | Harrisburg | B43 Education | $78.7M | 6 |
| Senior Health Properties - South Inc | Bala Cynwyd | P80Z Human Services | $78.3M | 11 |
| DOLLAR ENERGY FUND INC | Pittsburgh | L820 Housing & Shelter | $78.1M | 7 |
| THE REINVESTMENT FUND INC | Philadelphia | S200 Community Improvement & Capacity Building | $78M | 14 |
