| MYMICHIGAN MEDICAL CENTER ALPENA | Alpena | E22 Health Care | $294.8M | 12 |
| ASCENSION ST MARY'S HOSPITAL | Midland | E20 Health Care | $282.2M | 18 |
| MCLAREN PORT HURON | Port Huron | E220 Health Care | $277.8M | 14 |
| INTERNATIONAL UNION - UAW | Detroit | — | $273M | 19 |
| CREDIT UNIONS CHARTERED IN THE STATE OF MICHIGAN | Dearborn | — | $270.9M | 10 |
| GREAT LAKES ENERGY COOPERATIVE | Boyne City | — | $256.3M | 19 |
| MUNSON HEALTHCARE | Traverse City | — | $245M | 33 |
| PINE REST CHRISTIAN MENTAL HEALTH SERVICES | Grand Rapids | F310 Mental Health & Crisis Intervention | $230.8M | 17 |
| CHARLES STEWART MOTT FOUNDATION | Flint | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $228.3M | 9 |
| ST JOSEPH MERCY CHELSEA INC | Chelsea | E22 Health Care | $210.7M | 13 |
| NSF INTERNATIONAL | Ann Arbor | M05 Public Safety, Disaster Preparedness & Relief | $203.1M | 26 |
| MICHIGAN PUBLIC HEALTH INSTITUTE | Okemos | E21Z Health Care | $202.1M | 14 |
| MICHIGAN SCHOOLS AND GOVERNMENT CREDIT UNION | Clinton Township | — | $201.6M | 10 |
| PACE SOUTHEAST MICHIGAN F/K/A CENTER FOR SENIOR INDEPENDENCE | Southfield | E92 Health Care | $198.9M | 7 |
| ELLA E M BROWN CHARITABLE CIRCLE | Marshall | E220 Health Care | $191.5M | 10 |
| HOPE COLLEGE | Holland | B420 Education | $189.4M | 16 |
| MARY FREE BED REHABILITATION HOSPITAL | Grand Rapids | E240 Health Care | $188.7M | 12 |
| UNIVERSITY OF DETROIT MERCY | Detroit | B430 Education | $188.3M | 27 |
| NATIONAL ADVANCED MOBILITY CONSORTIUM INC | Ann Arbor | U40 Science & Technology | $187.6M | 6 |
| MYMICHIGAN MEDICAL GROUP | Midland | E80Z Health Care | $185.9M | 21 |
| CALVIN UNIVERSITY | Grand Rapids | B430 Education | $184.9M | 10 |
| HOPE NETWORK | Grand Rapids | L20 Housing & Shelter | $183.8M | 17 |
| CREDIT UNIONS CHARTERED IN THE STATE OF MICHIGAN | Kalamazoo | — | $183.1M | 11 |
| LAFCU | Lansing | — | $177.5M | 9 |
| FOOD BANK COUNCIL OF MICHIGAN INC | Lansing | — | $175.8M | 4 |
| TRINITY HOME HEALTH SERVICES | Livonia | E92Z Health Care | $174.7M | 13 |
| DELTA DENTAL PLAN OF INDIANA INC | Lansing | — | $174.3M | 6 |
| MIDWEST ENERGY COOPERATIVE | Cassopolis | K20 Food, Agriculture & Nutrition | $168.1M | 22 |
| MCLAREN LAPEER REGION | Lapeer | E220 Health Care | $164.2M | 11 |
| OPERATING ENGINEERS' LOCAL 324 HEALTH CARE PLAN | Troy | — | $161.8M | 4 |
| CONSUMERS CREDIT UNION | Kalamazoo | — | $160.6M | 17 |
| DORT FINANCIAL CREDIT UNION | Grand Blanc | — | $156.7M | 13 |
| SPARROW HEALTH SYSTEM | Lansing | E120 Health Care | $156M | 28 |
| UNIVERSITY PHYSICIAN GROUP | Detroit | E110 Health Care | $155.2M | 15 |
| MYMICHIGAN MEDICAL CENTER ALMA | Alma | E220 Health Care | $153.8M | 9 |
| Merit Network Inc | Ann Arbor | W50 Public & Societal Benefit | $153.2M | 26 |
| CREDIT UNIONS CHARTERED IN THE STATE OF 222 LAKE TRUST CREDIT UNION | Brighton | — | $146.4M | 18 |
| DICKINSON COUNTY HEALTHCARE SYSTEM | Iron Mountain | E20 Health Care | $144.3M | 4 |
| MARSHALL AREA ECONOMIC DEVELOPMENT | Marshall | C99 Environment | $143.7M | 1 |
| ADVANTAGE HEALTHSAINT MARY'S MEDICAL GROUP | Grand Rapids | E31 Health Care | $143.7M | 25 |
| KALAMAZOO COLLEGE | Kalamazoo | B420 Education | $143.1M | 13 |
| UNIVERSITY OF MICHIGAN HEALTH PLAN | East Lansing | — | $142.9M | 19 |
| MCLAREN CENTRAL MICHIGAN | Mt Pleasant | E220 Health Care | $142.7M | 11 |
| BETHANY CHRISTIAN SERVICES | Grand Rapids | — | $141.8M | 0 |
| MUNSON HEALTHCARE CADILLAC | Traverse City | E20 Health Care | $140.7M | 15 |
| VAN ANDEL INSTITUTE | Grand Rapids | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $139.3M | 6 |
| MYMICHIGAN MEDICAL CENTER SAULT | Sault Ste Marie | E220 Health Care | $137.3M | 23 |
| MICHIGAN FIRST CREDIT UNION | Lathrup Village | — | $136.4M | 16 |
| MUNSON HEALTHCARE OTSEGO MEMORIAL HOSPITAL | Gaylord | E22Z Health Care | $129.7M | 15 |
| COMMUNITY FOUNDATION FOR SOUTHEAST MICHIGAN | Detroit | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $128.2M | 13 |
