| MCLAREN PORT HURON | Port Huron | E220 Health Care | $277.8M | 14 |
| GREAT LAKES ENERGY COOPERATIVE | Boyne City | — | $256.3M | 19 |
| CREDIT UNIONS CHARTERED IN THE STATE OF MICHIGAN | Auburn Hills | — | $255.1M | 16 |
| MYMICHIGAN MEDICAL CENTER ALPENA | Alpena | E22 Health Care | $254.7M | 14 |
| CREDIT UNIONS CHARTERED IN THE STATE OF MICHIGAN | Dearborn | — | $237.7M | 11 |
| MUNSON HEALTHCARE | Traverse City | — | $215.1M | 33 |
| MYMICHIGAN HEALTH | Midland | E210 Health Care | $214.9M | 23 |
| MICHIGAN HEALTH & HOSPITAL ASSOCIATION | Okemos | — | $213.7M | 7 |
| PINE REST CHRISTIAN MENTAL HEALTH SERVICES | Grand Rapids | F310 Mental Health & Crisis Intervention | $205.8M | 19 |
| NSF INTERNATIONAL | Ann Arbor | M05 Public Safety, Disaster Preparedness & Relief | $203.1M | 26 |
| MICHIGAN SCHOOLS AND GOVERNMENT CREDIT | Clinton Township | — | $201.6M | 10 |
| ST JOSEPH MERCY CHELSEA INC | Chelsea | E22 Health Care | $201.6M | 16 |
| ELLA E M BROWN CHARITABLE CIRCLE | Marshall | E220 Health Care | $191.5M | 10 |
| CALVIN UNIVERSITY | Grand Rapids | B430 Education | $190.9M | 10 |
| MARY FREE BED REHABILITATION HOSPITAL | Grand Rapids | E240 Health Care | $188.7M | 12 |
| NATIONAL ADVANCED MOBILITY CONSORTIUM | Ann Arbor | U40 Science & Technology | $187.6M | 6 |
| HOPE NETWORK | Grand Rapids | L20 Housing & Shelter | $183.8M | 17 |
| CREDIT UNIONS CHARTERED IN THE | Kalamazoo | — | $183.1M | 11 |
| HOPE COLLEGE | Holland | B420 Education | $181.7M | 13 |
| MYMICHIGAN MEDICAL GROUP | Midland | E80Z Health Care | $178.4M | 23 |
| LAFCU | Lansing | — | $177.5M | 9 |
| UNIVERSITY OF DETROIT MERCY | Detroit | B430 Education | $176.1M | 27 |
| FOOD BANK COUNCIL OF MICHIGAN INC | Lansing | — | $175.8M | 4 |
| PACE SOUTHEAST MICHIGAN | Southfield | E92 Health Care | $171.8M | 7 |
| MICHIGAN PUBLIC HEALTH INSTITUTE | Okemos | E21Z Health Care | $165.3M | 14 |
| UNIVERSITY OF MICHIGAN HEALTH PLAN | East Lansing | — | $164.5M | 17 |
| MCLAREN LAPEER REGION | Lapeer | E220 Health Care | $164.2M | 11 |
| SPARROW HEALTH SYSTEM | Lansing | E120 Health Care | $162.3M | 27 |
| OPERATING ENGINEERS' LOCAL 324 HEALTH | Troy | — | $161.8M | 4 |
| MYMICHIGAN MEDICAL CENTER ALMA | Alma | E220 Health Care | $160.9M | 11 |
| CONSUMERS CREDIT UNION | Kalamazoo | — | $160.6M | 17 |
| UNIVERSITY PHYSICIAN GROUP | Detroit | E110 Health Care | $155.2M | 15 |
| TRINITY HOME HEALTH SERVICES | Livonia | E92Z Health Care | $154.3M | 13 |
| DELTA DENTAL PLAN OF INDIANA INC | Lansing | — | $153.6M | 7 |
| MARSHALL AREA ECONOMIC DEVELOPMENT | Marshall | C99 Environment | $151.6M | 0 |
| GLEANER LIFE INSURANCE SOCIETY | Adrian | — | $151.3M | 26 |
| MIDWEST ENERGY COOPERATIVE | Cassopolis | K20 Food, Agriculture & Nutrition | $146.6M | 21 |
| KALAMAZOO COLLEGE | Kalamazoo | B420 Education | $143.1M | 13 |
| MCLAREN CENTRAL MICHIGAN | Mt Pleasant | E220 Health Care | $142.7M | 11 |
| DICKINSON COUNTY HEALTHCARE SYSTEM | Iron Mountain | E20 Health Care | $142.1M | 13 |
| BETHANY CHRISTIAN SERVICES | Grand Rapids | — | $141.8M | 0 |
| MYMICHIGAN MEDICAL CENTER SAULT | Sault Ste Marie | E220 Health Care | $140M | 23 |
| VAN ANDEL INSTITUTE | Grand Rapids | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $139.3M | 6 |
| PHYSICIANS HEALTH NETWORK | East Lansing | E300 Health Care | $138.9M | 17 |
| CHARLES STEWART MOTT FOUNDATION | Flint | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $136.7M | 7 |
| MICHIGAN FIRST CREDIT UNION | Lathrup Village | — | $136.4M | 16 |
| MUNSON HEALTHCARE CADILLAC | Traverse City | E20 Health Care | $131.4M | 16 |
| ADVANTAGE HEALTHSAINT MARY'S | Grand Rapids | E31 Health Care | $129.3M | 28 |
| COMMUNITY FOUNDATION FOR SOUTHEAST | Detroit | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $128.2M | 13 |
| HONOR CREDIT UNION | Berrien Springs | — | $127.9M | 10 |
