| WESTERN MICHIGAN UNIVERSITY HOMER | Kalamazoo | B50 Education | $125.6M | 9 |
| CREDIT UNION CHARTERED IN THE STATE OF | Farmington Hills | — | $124.8M | 17 |
| CREDIT UNIONS CHARTERED IN THE STATE OF | Brighton | — | $121.9M | 19 |
| MCLAREN MEDICAL GROUP | Flint | E300 Health Care | $120.1M | 12 |
| DAVENPORT UNIVERSITY | Grand Rapids | B420 Education | $119.1M | 10 |
| ORGAN PROCUREMENT AGENCY OF MICHIGAN | Ann Arbor | — | $117.9M | 12 |
| DOW CREDIT UNION | Midland | — | $117.1M | 11 |
| MUNSON HEALTHCARE OTSEGO MEMORIAL | Gaylord | E22Z Health Care | $116.1M | 16 |
| GLEANERS COMMUNITY FOOD BANK | Detroit | K31 Food, Agriculture & Nutrition | $116.1M | 11 |
| MCLAREN HEALTH MANAGEMENT GROUP | Davison | E32 Health Care | $114.2M | 10 |
| VAN ANDEL RESEARCH INSTITUTE | Grand Rapids | H300 Medical Research | $112.7M | 15 |
| MICHIGAN HEALTH ENDOWMENT FUND | Brighton | G12 Diseases, Disorders & Medical Disciplines | $112.3M | 12 |
| WAYNE-METROPOLITAN COMMUNITY | Detroit | S200 Community Improvement & Capacity Building | $112.2M | 10 |
| HOMELESS ACTION NETWORK OF DETROIT | Detroit | P80 Human Services | $109.6M | 0 |
| ELGA CREDIT UNION | Grand Blanc | — | $108.7M | 10 |
| DORT FINANCIAL CREDIT UNION | Grand Blanc | — | $107.6M | 12 |
| DETROIT AREA AGENCY ON AGING | Detroit | P81Z Human Services | $105M | 7 |
| ADRIAN COLLEGE | Adrian | B420 Education | $104.8M | 7 |
| KETTERING UNIVERSITY | Flint | B500 Education | $104.3M | 13 |
| UNIVERSITY PEDIATRICIANS | Detroit | E31 Health Care | $104.2M | 7 |
| SAMARITAS | Detroit | P200 Human Services | $104M | 10 |
| MSU HEALTH CARE INC | East Lansing | E30 Health Care | $103.2M | 20 |
| FORGOTTEN HARVEST INC | Oak Park | K31M Food, Agriculture & Nutrition | $101.8M | 13 |
| ANDREWS UNIVERSITY | Berrien Springs | B430 Education | $101.7M | 11 |
| PENSKE FOUNDATION INC | Bloomfield Hills | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $101.5M | 0 |
| ALBION COLLEGE | Albion | B420 Education | $100.6M | 13 |
| Community Financial Credit Union | Plymouth | — | $100M | 15 |
| MHT HOUSING INC | Bingham Farms | L200 Housing & Shelter | $99.4M | 8 |
| W E UPJOHN UNEMPLOYMENT TRUSTEE CORP | Kalamazoo | J220 Employment | $98.3M | 11 |
| Northwood University | Midland | B430 Education | $98M | 13 |
| Wolverine Power Marketing Cooperative | Cadillac | Y22 Mutual & Membership Benefit | $96.8M | 9 |
| MICHIGAN LIFE AND HEALTH INSURANCE | Haslett | — | $94.9M | 0 |
| COLLEGE FOR CREATIVE STUDIES | Detroit | B420 Education | $94.5M | 12 |
| MUNSON HEALTHCARE GRAYLING | Traverse City | E20 Health Care | $94.5M | 16 |
| HELPING HAND FOR RELIEF AND DEVELOPMENT INC | Southfield | P60 Human Services | $94M | 7 |
| Bronson Lakeview Hospital | Kalamazoo | E20 Health Care | $94M | 16 |
| UNITED WAY FOR SOUTHEASTERN MICHIGAN | Detroit | M20 Public Safety, Disaster Preparedness & Relief | $93.1M | 9 |
| MACOMB-OAKLAND-REGIONAL CENTER INC | Clinton Township | P800 Human Services | $93.1M | 2 |
| MICHIGAN REGIONAL COUNCIL OF | Troy | Y43 Mutual & Membership Benefit | $92.7M | 5 |
| LAWRENCE TECHNOLOGICAL UNIVERSITY | Southfield | B430 Education | $92.2M | 13 |
| UNIVERSITY OF MICHIGAN HEALTH | East Lansing | E70 Health Care | $91.2M | 14 |
| CLOVERLAND ELECTRIC COOPERATIVE | Sault Ste Marie | — | $90.7M | 17 |
| CRANBROOK EDUCATIONAL COMMUNITY | Bloomfield Hills | B200 Education | $90.6M | 14 |
| GREAT LAKES BAY HEALTH CENTERS | Saginaw | E320 Health Care | $89.4M | 16 |
| Holland Home | Grand Rapids | P70Z Human Services | $88.8M | 8 |
| VIBE CREDIT UNION | Novi | — | $87.4M | 21 |
| ALMA COLLEGE | Alma | B420 Education | $87M | 15 |
| CREDIT UNIONS CHARTERED IN THE STATE OF | Frankenmuth | — | $86.4M | 8 |
| Michigan Laborers Health Care Fund | Lansing | — | $86.4M | 5 |
| CHERRY STREET SERVICES INC | Grand Rapids | E320 Health Care | $85.1M | 7 |
