| OREGON STATE CREDIT UNION | Corvallis | — | $144.1M | 24 |
| OREGON HEALTH & SCIENCE UNIVERSITY FOUNDATION | Portland | B110 Education | $140.6M | 13 |
| SELCO Community Credit Union | Springfield | — | $139.8M | 8 |
| SILVERTON HEALTH DBA LEGACY SILVERTON HEALTH | Silverton | E220 Health Care | $138.9M | 27 |
| Mid-Columbia Medical Center | The Dalles | E220 Health Care | $135.8M | 19 |
| OREGON FOOD BANK | Portland | — | $132.2M | 9 |
| Northwest Medical Foundation Tillamook | Tillamook | E220 Health Care | $127.6M | 24 |
| SALEM HEALTH HOSPITALS & CLINICS | Salem | — | $119.7M | 2 |
| CITY FUND | Beaverton | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $118.6M | 8 |
| ST ANTHONY HOSPITAL | Pendleton | E220 Health Care | $113.6M | 10 |
| Linfield University | McMinnville | B420 Education | $110.2M | 9 |
| SCHOOL DISTRICT NO 1 HEALTH AND WELFARE TRUST FUND | Tualatin | — | $106.7M | 0 |
| GREATER OREGON BEHAVIORAL HEALTH INC | The Dalles | E80 Health Care | $105.7M | 13 |
| RIVERMARK COMMUNITY CREDIT UNION | Oregon City | — | $104.2M | 39 |
| CASCADIA HEALTH | Portland | F300 Mental Health & Crisis Intervention | $103.7M | 24 |
| United Association Union Local No 290 Plumber Steamfitter and Shipfitter Industry H&W Plan | Tualatin | — | $103.5M | 0 |
| SALEM HEALTH WEST VALLEY | Dallas | E22 Health Care | $101.2M | 8 |
| VIRGINIA GARCIA MEMORIAL HEALTH CENTER | Aloha | E32Z Health Care | $100.5M | 23 |
| ADVANTIS CREDIT UNION | Oregon City | — | $98.7M | 27 |
| SAMARITAN NORTH LINCOLN HOSPITAL | Lincoln City | E22 Health Care | $94.6M | 12 |
| UNITUS COMMUNITY CREDIT UNION | Tigard | — | $90.9M | 32 |
| MARION AND POLK SCHOOLS CREDIT UNION | Salem | — | $89.9M | 24 |
| Oregon Child Development Coalition | Wilsonville | P84Z Human Services | $84.2M | 8 |
| The Ford Family Foundation | Roseburg | T50 Philanthropy, Voluntarism & Grantmaking Foundations | $81.2M | 10 |
| RIDE CONNECTION INC | Portland | P52Z Human Services | $80M | 9 |
| MEDICAL TEAMS INTERNATIONAL | Tigard | Q300 International, Foreign Affairs & National Security | $79.4M | 8 |
| SAINT ALPHONSUS MEDICAL CENTER - ONTARIO INC | Ontario | E20 Health Care | $79.3M | 9 |
| CENTRAL ELECTRIC COOPERATIVE | Redmond | — | $78.6M | 16 |
| ADAPT | Roseburg | — | $73.1M | 6 |
| FIRST COMMUNITY CREDIT UNION | Coquille | W61 Public & Societal Benefit | $71.1M | 21 |
| TRILLIUM FAMILY SERVICES | Portland | L99 Housing & Shelter | $71M | 9 |
| MOSAIC COMMUNITY HEALTH | Bend | E30 Health Care | $70.9M | 9 |
| Options for Southern Oregon | Grants Pass | F33Z Mental Health & Crisis Intervention | $70.4M | 16 |
| CENTENNIAL MEDICAL GROUP INC | Roseburg | E30 Health Care | $66M | 10 |
| ROGUE VALLEY MANOR | Medford | P75 Human Services | $65.3M | 7 |
| MID WILLAMETTE VALLEY COMMUNITY ACTION AGENCY | Salem | — | $61.1M | 4 |
| RELAY RESOURCES | Portland | J300 Employment | $60.9M | 10 |
| ASANTE PHYSICIAN PARTNERS | Medford | E80 Health Care | $60.8M | 17 |
| LA CLINICA DEL VALLE FAMILY HEALTH CARE CENTER INC | Medford | — | $60.7M | 8 |
| THE IMMIGRANT AND REFUGEE COMMUNITY ORGANIZATION | Portland | — | $60.4M | 2 |
| OREGON TRAIL ELECTRIC CONSUMERS COOPERATIVE INC | Baker City | — | $59.7M | 19 |
| NATIVE AMERICAN REHABILITATION ASSOCIATION OF THE NORTHWEST INC | Portland | F220 Mental Health & Crisis Intervention | $59.5M | 17 |
| Oregon Homecare Workers Supplemental Trust | Portland | E03 Health Care | $57.5M | 0 |
| COLUMBIACARE SERVICES INC | Medford | F31 Mental Health & Crisis Intervention | $57.2M | 18 |
| OREGON ESSENTIAL WORKFORCE HEALTH CARE FUND | Portland | Y43 Mutual & Membership Benefit | $57M | 0 |
| ST VINCENT DE PAUL SOCIETY OF LANE COUNTY INC | Eugene | P200 Human Services | $56M | 8 |
| MULTNOMAH ATHLETIC CLUB | Portland | — | $56M | 12 |
| COMMUNITY COUNSELING SOLUTIONS | Heppner | F32 Mental Health & Crisis Intervention | $54.2M | 7 |
| Community Action Organization | Hillsboro | P80Z Human Services | $53.7M | 3 |
| LIFEWORKS NW | Portland | F30Z Mental Health & Crisis Intervention | $53.7M | 7 |
