| THE GOOD SAMARITAN HOSPITAL OF LEBANON | York | E220 Health Care | $286.1M | 18 |
| University of Scranton | Scranton | B430 Education | $278.9M | 18 |
| The Washington Hospital | Washington | E220 Health Care | $276.6M | 10 |
| Elwyn of Pennsylvania and Delaware | Elwyn | P820 Human Services | $275.4M | 15 |
| CLINICAL CARE ASSOCIATES OF THE | Bala Cynwyd | E300 Health Care | $274.2M | 18 |
| SWARTHMORE COLLEGE | Swarthmore | B420 Education | $270.7M | 24 |
| Temple University Health System Inc | Philadelphia | B19 Education | $269.9M | 17 |
| DELAWARE COUNTY PUBLIC SCHOOLS | Morton | Y20 Mutual & Membership Benefit | $265.8M | 0 |
| EVANGELICAL COMMUNITY HOSPITAL | Lewisburg | E220 Health Care | $259.6M | 19 |
| LAFAYETTE COLLEGE | Easton | B420 Education | $259M | 18 |
| BRYN MAWR COLLEGE | Bryn Mawr | B420 Education | $254.6M | 17 |
| PENNSYLVANIA LIFE & HEALTH | Bala Cynwyd | — | $250.6M | 1 |
| Grand View Hospital | Sellersville | E22 Health Care | $250M | 17 |
| MEADVILLE MEDICAL CENTER | Meadville | E220 Health Care | $249.6M | 12 |
| SUN COAST NURSING CENTERS INC | Bala Cynwyd | E90 Health Care | $249.5M | 9 |
| Riddle Memorial Hospital | Newtown Square | E220 Health Care | $248.7M | 40 |
| WIDENER UNIVERSITY | Chester | B430 Education | $243.6M | 16 |
| PHI GROUP RETURN | Dillsburg | — | $241.9M | 22 |
| GEISINGER-LEWISTOWN HOSPITAL | Danville | E220 Health Care | $238.5M | 16 |
| Northeast Behavioral Health Care Consort | Moosic | F80 Mental Health & Crisis Intervention | $233.9M | 4 |
| MASONIC VILLAGES OF THE GRAND LODGE | Elizabethtown | L50 Housing & Shelter | $232.2M | 23 |
| COMMUNITY SERVICES FOR CHILDREN INC | Allentown | B22Z Education | $230.5M | 12 |
| CONSTELLATION EMPLOYEES BENEFIT | Kennett Square | Y43 Mutual & Membership Benefit | $228.8M | 1 |
| GETTYSBURG COLLEGE | Gettysburg | B420 Education | $228.8M | 18 |
| MERCY CATHOLIC MEDICAL CENTER OF | Newtown Square | E220 Health Care | $226.2M | 15 |
| TOWER HEALTH MEDICAL GROUP | Reading | — | $225.3M | 12 |
| ST LUKE'S HOSPITAL MONROE CAMPUS | Allentown | E22 Health Care | $225.2M | 3 |
| MAIN LINE SERVICES | Newtown Square | — | $224.9M | 29 |
| DICKINSON COLLEGE | Carlisle | B420 Education | $221.6M | 18 |
| THE PENNSYLVANIA CYBER CHARTER SCHOOL | Midland | B29 Education | $220.9M | 13 |
| INDIANA REGIONAL MEDICAL CENTER | Indiana | E22 Health Care | $218M | 15 |
| UPMC HANOVER | Harrisburg | E220 Health Care | $215.6M | 11 |
| CORPORATION OF HAVERFORD COLLEGE | Haverford | B420 Education | $211.7M | 19 |
| RICHARD KING MELLON FOUNDATION | Ligonier | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $210.9M | 5 |
| EMPLOYEE BENEFIT TRUST OF BANK OF | Pittsburgh | Y43 Mutual & Membership Benefit | $206.4M | 0 |
| ST LUKE'S WARREN HOSPITAL INC | Allentown | E220 Health Care | $204.9M | 10 |
| Uniontown Hospital | Uniontown | E20 Health Care | $204.2M | 16 |
| UPMC Memorial | Harrisburg | E220 Health Care | $203.9M | 15 |
| UPMC Pinnacle | Harrisburg | E220 Health Care | $201.7M | 15 |
| LAKE ERIE COLLEGE OF OSTEOPATHIC | Erie | B500 Education | $201.5M | 13 |
| TRUMARK FINANCIAL CREDIT UNION | Fort Washington | — | $198.1M | 26 |
| FRANKLIN & MARSHALL COLLEGE | Lancaster | B420 Education | $187M | 17 |
| DISTRICT COUNCIL 33 HEALTH -WELFARE FUND | Philadelphia | — | $183M | 15 |
| GROVE CITY COLLEGE | Grove City | B420 Education | $178.5M | 14 |
| PHILADELPHIA HOUSING DEVELOPMENT CORPORA | Philadelphia | L250 Housing & Shelter | $178.2M | 7 |
| PNC FOUNDATION | Pittsburgh | — | $177.6M | 0 |
| DIAKON LUTHERAN SOCIAL MINISTRIES | Topton | L22 Housing & Shelter | $177.4M | 11 |
| CONCORDIA LUTHERAN MINISTRIES | Cabot | E11 Health Care | $176.9M | 3 |
| JOHN TEMPLETON FOUNDATION | West Conshohocken | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $175.8M | 17 |
| KEYSTONE SERVICE SYSTEMS INC | Harrisburg | P730 Human Services | $174.5M | 9 |
